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Remarkably, 2 keeps an unusual, totally different binding form, making use of the fluorine accepting an H-bond from Leu83NH (Figure 3)

Remarkably, 2 keeps an unusual, totally different binding form, making use of the fluorine accepting an H-bond from Leu83NH (Figure 3) To research whether either the bicyclic center or even the fluorophenyl people had been accountable for the strange joining function, 3D-structures are determined for 2 early analogs of 2. Both the IP 3 and…